Our Mission For over 30 years, Thorne Research has been dedicated to enhancing the health and well-being of people worldwide by providing innovative, high-quality, research-based nutritional supplements, health diagnostics technology platforms, and the latest in medical education. Through our products and services, our passionate, talented staff, collaboration with a variety of innovative and expert strategic partners, and an unwavering commitment to integrity, Thorne Research strives to become a leading health-care company serving people around the world.

active, tissue-ready form of vitamin B5

• the active form of vitamin B5 is readily used by the body*
• promotes healthy cholesterol metabolism*
• supports adrenal function*
• Pantethine is not derived from yeast

Pantethine is the stable, metabolically active form of pantothenic acid, or vitamin B5.* Pantethine is a vital component of coenzyme A, a cofactor for dozens of enzymatic reactions, including those involved with fat and carbohydrate metabolism.* Clinical trials suggest that, because its biochemical configuration is closer to coenzyme A than pantothenic acid, pantethine may have more benefit than pantothenic acid.* Pantethine appears to help metabolize fatty acids by activation of coenzyme A, promotion of carnitine transport of fatty acids into the mitochondria, and subsequent intra-mitochondrial oxidation of fatty acids.* All of these help improve energy production in every cell of the body.*

Consequently, pantethine supplementation has been found to support good cardiovascular health.* In addition, increases in beneficial HDL cholesterol and apolipoprotein A1 have been noted in association with pantethine supplementation.* Apolipoprotein A1 is the major protein component of HDL and promotes cholesterol removal from tissues to the liver for excretion.*

Pantethine is also considered the "anti-stress" vitamin because it supports healthy adrenal cortex function and hormone synthesis, particularly during times of stress.* Pantothenic acid deficiency can result in adrenal atrophy, which is characterized by increased fatigue, sleep disturbances, nausea, and abdominal discomfort.*